The series, written by Stephen M. Irwin and created and produced by Leigh McGrath, was the first international drama production for the Disney-owned ABC Studios International, which teamed up on the project with Hoodlum Entertainment, the Australian Broadcasting Corporation and Screen Queensland. The location is Brisbane, including the offices and laboratories in the heritage-listed former Brisbane Dental Hospital and College. On 2 May 2018, ABC announced that they had commissioned a second series, with filming set to begin in September 2018. The second series began airing on 12 May 2019. On 10 October 2019 ABC renewed the programme for a third series with filming set to begin in November 2019 and confirmed Ioan Gruffudd would direct an episode.